Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0333772
PubChem CID
Molecular Formula
C21H22N2O
Molecular Weight
318.42 g/mol
Synonyms/Alias
N/A (Not available)
InChI Key
DFUGSIMXDLGFTF-UHFFFAOYSA-N
InChI
InChI=1S/C21H22N2O/c24-21(22-18-10-2-1-3-11-18)23-19-12-6-4-8-16(19)14-15-17-9-5-7-13-20(17)23/h4-9,...
IUPAC Name
N-cyclohexylbenzo[b][1]benzazepine-11-carboxamide
CAS Number
N/A (Not available)

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

46 49 0 0 0 0 0 0 0 0999 V2000
0.3767 -1.0251 1.8097 O 0 0 0 0 0 0 0 0 0 0 0 0
0.0252 -0.3406 0.8095 C 0 0 0 0 0 0 0 0 0 0 0 0
0.9126 0.666...

Experimental Data

Activity Data

Target Ion Channel
P2X purinoceptor 4
Uniprot Accession Number
Function
Blocker
Species
Rattus norvegicus (Rat)
IC50
IC50: 109000 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.4
Holding Potential
Not specified
Temperature
23 ℃
Test Method
Fluorometric Imaging Plate Reader (FLIPR) Membrane Potential Assay (Calcium ion)
Test Species
1321 N1 astrocytoma cell

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
24
Rotatable Bonds
1
logP
5.3508
Complexity
99.3557
TPSA (Ų)
32.34
H-Bond Donors
1
H-Bond Acceptors
1
Ring Count
4
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